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Pharma - your Formulation Development Options ... - together



DSM Research has developed Micro-Compounders, Injection Molding Machines, and technology specifically designed for drug development studies. In your quest to identify and develop promising active pharmaceutical ingredients (APls) into the next blockbuster product for your company, two factors must be minimized to ensure success:

time to market
development costs

Questions you might have...

  • How long does it take you to compound an API and create a tablet or capsule to be used for dissolution testing, bio-availability studies, or stability studies
  • Are the number and size of your development batches by the cost and /or the availability of the API used
  • What if you could conduct your studies using less API material
  • What if you could compound and manufacture a sample in minutes using only grams of materials

Answers

DSM Research offers Micro-Compounders that are small, cost effective and minimize the use of API. The core of these Micro-Compounder's are the fluid proof mixing compartment containing two conical mixing screws. Both the compartment and the mixing screws are specially treated to make them chemicals resistant. The mixing is digitally controlled for torque and temperature, resulting in superb dispersion preventing agglomeration. Micro-Compounders are available in sizes that can disperse and extrude 5 or 15 of your test formula. DSM Research's Injection Molding Machines (right) are built based on the same leading edge technology, utilizing batch sizes of 3,5 or 10 ml. Material prepared from the compounder is injected directly into conical shaped molds of
your design using a mechanical plunger powered by compressed air. Several sample tablets or capsules can be manufactured at one time in less than 4 minutes.